Erythromycin A 11,12-methylene acetal.
نویسندگان
چکیده
Erythromycin A 11,12-methylene acetal (5) and the corresponding 9-methoxime, 9-dihydro, and 8-hydroxy derivatives have been prepared and their antibacterial activities compared with those of erythromycin A and its 11,12-cyclic carbonate. The simple methylene acetal 5 showed excellent activity against Gram-positive organisms in vitro.
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ورودعنوان ژورنال:
- The Journal of antibiotics
دوره 41 11 شماره
صفحات -
تاریخ انتشار 1988